He was replaced in an upcoming movie because of his substance abuse issues

This A list mostly movie actor at least when it comes to his franchise larger than life character was replaced in an upcoming movie because of his substance abuse issues.

Henry Cavill – Superman
Dominic Cooper Replaces Henry Cavill in Action-Thriller “Stratton”
http://variety.com/2015/film/news/dominic-cooper-replacing-henry-cavill-stratton-1201536838/

Source: http://www.crazydaysandnights.net